Too much calcium in the blood can cause weakness, lead to kidney stones, and interfere with the heart and brain, and even be life threatening. Hypercalcemia, or high blood calcium, can occur when there are very high levels of vitamin D in the blood. Thacher, M.D., a family medicine expert at Mayo Clinic. "We found that even in those with high levels of vitamin D over 50 ng/mL, there was not an increased risk of hypercalcemia, or elevated serum calcium, with increasing levels of vitamin D," says study co-author Thomas D. Of 20,308 measurements, 8 percent of the people who had their vitamin D measured had levels greater than 50 ng/mL, and less than 1 percent had levels over 100 ng/mL. MEDIA CONTACT: Sharon Theimer, Mayo Clinic Public Affairs, 50, Email: researchers analyzed data collected between 20 from patients in the Rochester Epidemiology Project, a National Institutes of Health-funded medical records pool that makes Olmsted County, Minn., the home of Mayo Clinic, one of the few places worldwide where scientists can study virtually an entire geographic population to identify health trends. A normal level is 20-50 ng/mL, and deficiency is considered anything less than 20 ng/mL, according the Institute of Medicine (IOM). Vitamin D levels are determined by a blood test called a serum 25-hydroxyvitamin D blood test. Their study appears in the May issue of Mayo Clinic Proceedings.Ī vitamin D level greater than 50 nanograms per milliliter is considered high. They found that toxic levels are actually rare. In light of the increased use of vitamin D supplements, Mayo Clinic researchers set out to learn more about the health of those with high vitamin D levels. Vitamin D has been shown to boost bone health and it may play a role in preventing diabetes, cancer, cardiovascular disease and other illnesses. Over the past decade, numerous studies have shown that many Americans have low vitamin D levels and as a result, vitamin D supplement use has climbed in recent years.
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